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No more Breath-Holding? new lung scan tested for patients on breathing support

NCT ID NCT07489950

Diagnosis Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new method to measure lung blood flow using electrical impedance tomography (EIT) without requiring patients to hold their breath. Twenty-four adults on respiratory support will receive a salt-water injection and have their lungs scanned during normal breathing and during a brief breath-hold. The goal is to see if the no-breath-hold method gives results as accurate as the standard breath-hold method, which could make lung monitoring safer and easier for critically ill patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
saline (salt water) injection
What this could lead to
If successful, this could allow doctors to monitor lung blood flow in patients who cannot hold their breath, improving safety and comfort during critical care.
What could go wrong
This is a small, early-stage study with only 24 participants. The new method may not match the accuracy of the standard breath-hold technique, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

24 people

The number who actually took part.

Started

Mar 2026

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged ≥ 18 years. Requiring respiratory support including Nasal Cannula, High-Flow Nasal Oxygen (HFNO), or Pressure Support Ventilation (PSV). Hemodynamically stable. Able to tolerate a brief respiratory pause (for the reference group). Signed informed consent. Exclusion Criteria: * Pregnancy or breastfeeding. Contraindications to electrical impedance tomography (e.g., cardiac pacemaker, skin integrity issues on the chest). Severe circulatory failure or cardiogenic shock. Known allergy to hypertonic saline.

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Conditions

The condition(s) this trial relates to.

Critical Illness respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Critical illness Pulmonary perfusion Respiratory insufficiency Ventilation-perfusion ratio

Contacts and locations

Locations

  • Department of Critical Care Medicine，Ruijin Hospital，Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, 200025, China

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