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New vaccine aims to stop lung cancer from coming back

NCT ID NCT05642195

First seen Sep 30, 2025 · Last updated Jun 14, 2026 · Updated 39 times

Summary

This study tests a vaccine made from lung cancer cells, combined with an immune-boosting drug (N-803), in people who have had surgery for non-small cell lung cancer and whose tumors are PD-L1 negative. The goal is to see if the vaccine can train the immune system to recognize and destroy any remaining cancer cells, preventing the cancer from returning. About 30 adults with no signs of cancer after surgery will receive the vaccine with or without N-803 over several months and be followed for up to 5 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

The condition(s) this trial relates to.

carcinoma Neoplasm, Residual non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.