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New program aims to help FDNY firefighters kick the habit for good

NCT ID NCT05997225

Disease control Sponsor: Albert Einstein College of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an enhanced tobacco cessation program for retired FDNY firefighters who smoke. The program automatically enrolled participants in counseling, tailored the advice based on their lung scans and breathing tests, and started a quit-smoking medication (varenicline) earlier than usual. The goal was to see if this approach would get more people to join the program and successfully quit smoking compared to standard care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
varenicline
What this could lead to
If successful, this approach could help more high-risk smokers quit, reducing their chance of lung cancer.
What could go wrong
This was a very small pilot study (23 participants) in a specific group (retired FDNY firefighters), so results may not apply to the general population. The intervention is complex and may not be easy to scale.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

23 people

The number who actually took part.

Started

May 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Enrolled in FDNY World Trade Center Health Program (WTCHP) * Retired * Age ≥ 50 years old * Self-reported current smoker on most recent questionnaire OR self-reported current smoker in the past 5 years * 20 pack-year smoker OR 20-year smoking duration Exclusion Criteria * Reduced renal function * estimated glomerular filtration rate (eGFR) \<30 \[CKD-EPI Creatinine Equation (2021)\] at last World Trade Center (WTC) medical monitoring blood exam OR ICD10 codes for kidney disease: N04.9, N17.9, N18.9, Z94.0, E13.21, N18.9, I12.9, N00.9, N03.9 * Undergoing active cancer treatment, defined as being diagnosed on 1/1/2022 or later * Clinical instability (e.g., hospitalization in last 3 months) * Using varenicline in last 30 days * Endorsing suicidal ideations: moderate or high risk on Columbia-Suicide Severity Rating Scale (C-SSRS) * Screened for alcohol use disorder AUDIT\>15

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Conditions

The condition(s) this trial relates to.

nicotine dependence Tobacco Smoking Tobacco Use Tobacco Use Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tobacco smoking Tobacco use Tobacco use cessation

Contacts and locations

Locations

  • FDNY World Trade Center Health Program

    Brooklyn, New York, 11201, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.