New CT scan could sharpen lung valve surgery for emphysema
NCT ID NCT05816239
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a special type of CT scan (dual-energy CT) can provide useful information for planning lung valve placement in people with emphysema. Researchers enrolled 13 adults who were already scheduled for the valve procedure. The goal was to see if the scan could measure changes in lung blood flow and function, potentially helping doctors place valves more accurately.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could show that dual-energy CT provides better images to guide lung valve placement, potentially improving outcomes for emphysema patients.
- What could go wrong
- This is a very small, early study with only 13 participants. It only tests imaging, not a treatment, so any benefit is indirect and uncertain.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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13 people
The number who actually took part.
- Started
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Feb 2023
- Finished
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May 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Up to 30 patients within the University Hospitals Health System
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients (≥ 18 years of age at the time of written informed consent) with emphysema who have been deemed appropriate candidates for bronchoscopic lung volume reduction Exclusion Criteria: * Patients unable to provide consent * Patients who are pregnant or nursing * Women of child-bearing age will undergo pregnancy tests based on University Hospital (UH) standard bronchoscopy pre-procedural testing * Patients unable to undergo a DECT chest (contraindications to a CT chest with intravenous contrast such as a reported or documented allergy to intravenous (IV) contrast or impaired renal function, defined as the following: * Glomerular filtration rate (GFR) \<90 ml/min/1.73 m2 at the time of initial evaluation if patient age is ≤ 59 years * GFR \<85 ml/min/1.73 m2 if patient age is 60-69 years * GFR \<75 ml/min/1.73 m2 if patient age is ≥70 years
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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