Does scar tissue help or hurt after disc replacement? new study investigates
NCT ID NCT04641039
First seen Mar 23, 2026 · Last updated Jun 23, 2026 · Updated 11 times
Summary
This study looks at what happens after a damaged disc in the lower back is replaced with an artificial one. Surgeons must remove part of the disc's outer ring to implant the new disc, and this may affect how the spine moves. The study will check if scar tissue that forms after surgery helps control extra movement, and whether repairing the ring during surgery leads to better results. Twenty-four adults aged 18 to 50 with chronic low back pain will be followed for a year.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital General Universitario de Valencia
RECRUITINGValencia, Valencia, 46014, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lumbar disc prosthesis
What this could lead to
If successful, this could help surgeons improve lumbar disc replacement procedures, potentially leading to better long-term spine function and less pain.
What could go wrong
This is a small, early-stage study with only 24 participants, so results may not apply to everyone. The procedure involves surgery risks like infection or scar tissue formation.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.