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PAH drug study halted: LTP001 fails to show promise

NCT ID NCT05135000

First seen Jan 14, 2026 · Last updated May 24, 2026 · Updated 16 times

Summary

This study tested an experimental drug called LTP001 in 47 people with pulmonary arterial hypertension (PAH), a condition where high blood pressure in the lungs makes it hard to breathe. The goal was to see if the drug could improve blood flow and exercise ability. The study was stopped early, and results were not strong enough to continue development.

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Contacts and locations

Locations

  • Medical Univ of South Carolina

    Charleston, South Carolina, 29425, United States

  • Novartis Investigative Site

    Caba, Buenos Aires, C1025ABI, Argentina

  • Novartis Investigative Site

    Berlin, 13353, Germany

  • Novartis Investigative Site

    Dresden, 01307, Germany

  • Novartis Investigative Site

    Heidelberg, 69120, Germany

  • Novartis Investigative Site

    Amsterdam, 1081 HV, Netherlands

  • Novartis Investigative Site

    Krakow, 31 202, Poland

  • Novartis Investigative Site

    Lodz, 91-347, Poland

  • Novartis Investigative Site

    Wroclaw, 50-556, Poland

  • Novartis Investigative Site

    Málaga, Andalusia, 29010, Spain

  • Novartis Investigative Site

    Barcelona, Catalonia, 08036, Spain

  • Novartis Investigative Site

    Madrid, 28041, Spain

  • Novartis Investigative Site

    Sheffield, South Yorkshire, S10 2JF, United Kingdom

  • Novartis Investigative Site

    London, SW3 6PH, United Kingdom

  • Pulmonary Associates PA

    Mesa, Arizona, 85206, United States

Conditions

Explore the condition pages connected to this study.