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Blood test before heart surgery may flag risk of dangerous heart rhythm

NCT ID NCT07737444

Knowledge-focused Sponsor: Anthony Tang Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

About one in three people who have open-heart surgery develop an irregular heartbeat called postoperative atrial fibrillation (POAF), which raises the risk of stroke and other complications. This study is testing whether a blood marker called lipoprotein(a), or Lp(a), can identify patients at higher risk. Adults scheduled for heart surgery will have their Lp(a) levels measured and will wear a chest monitor for three months after surgery to track heart rhythm. Small heart tissue samples taken during surgery will also be examined for scarring and inflammation, which may help explain how Lp(a) contributes to abnormal rhythms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If elevated Lp(a) is linked to a higher risk of postoperative atrial fibrillation, this could help identify high-risk patients before heart surgery and guide preventive monitoring or treatments.
What could go wrong
This is a small observational study with only 20 participants, so results may not apply to all heart surgery patients. The study looks for an association, not a proven cause.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients undergoing elective and urgent cardiac surgery with no history of persistent atrial fibrillation.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Scheduled for elective or urgent CABG, valve replacement, or combined CABG and valve replacement * Willing to wear the Skiin chest band for the duration of the study * Have a smartphone with an Operating System compatible with the * Skiin Connected Life App (Android 9+ or iOS 13+) Exclusion Criteria: * Emergency indication for CABG, valve replacement, or combined CABG and valve replacement * Prior cardiac surgery * History of pre-operative persistent atrial fibrillation

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Conditions

The condition(s) this trial relates to.

atrial fibrillation Fibrosis Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial fibrillation (AF) POAF

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

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