Leg exercises may boost strength in schizophrenia patients with muscle wasting
NCT ID NCT07183969
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether a 16-week lower body strength training program could improve physical performance in people with chronic schizophrenia who also have sarcopenia (muscle loss). 78 participants from a psychiatric hospital in Taiwan were split into two groups: one did leg exercises, the other received usual care. Researchers measured balance, walking speed, chair stand ability, quality of life, and falls. The goal was to see if exercise could slow muscle decline and help patients stay independent.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lower limb muscle strength training program (plyometric exercises)
- What this could lead to
- If effective, this simple exercise program could become a non-drug way to help people with chronic schizophrenia maintain strength and independence.
- What could go wrong
- This is a small, completed study with only 78 participants, so results may not apply broadly. The exercises require supervision and may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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78 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Jan 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * (1) Suitable for participation in this study as assessed by the attending physician. * (2) After explaining the purpose of the study and the study process, family members and study subjects were asked to agree to participate in the study and to complete the consent form for signature. Exclusion Criteria: * (1) Those who are unable to walk unaided. * (2) Severe structural disability that prevents the performance of lower extremity training. * (3) Those with severe psychiatric symptoms that prevent them from concentrating and following instructions. * (4)Participation in a lower extremity muscle training program or intervention within one year.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tsaotun Psychiatric Center,MOHW
Tsaotun, Nanton, 542, Taiwan