Cutting radiation in CT scans: can AI-Powered denoising keep images sharp?
NCT ID NCT07759050
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This study tests whether chest and abdominal CT scans taken at a lower radiation dose, enhanced with a technology called Spectral Precise Image (SPI) intelligent denoising, can produce images as clear as standard-dose scans. About 80 healthy adult volunteers will receive both low-dose and routine-dose scans, and radiologists will compare image quality and noise levels. The goal is to see if lower radiation exposure can be used without compromising the clarity needed for accurate diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Low-dose CT radiation scan with Spectral Precise Image (SPI) intelligent denoising
- What this could lead to
- If successful, this could enable lower radiation exposure for chest and abdominal CT scans without sacrificing image clarity, potentially improving patient safety.
- What could go wrong
- The trial is small (80 participants) and focuses on image quality rather than clinical outcomes, so results may not apply broadly or guarantee diagnostic accuracy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years. * 18.5 kg/m² ≤ BMI \< 28 kg/m². * Conscious, able to cooperate, and competent to perform study procedures. * Voluntarily agrees to participate in this clinical study and has signed the informed consent form. * Women of childbearing potential must have a negative pregnancy test and have no plans to become pregnant during the next 6 months. Exclusion Criteria: * Persons without full civil capacity. * Pregnant or breastfeeding women. * Any other conditions that, in the investigator's judgment, make the subject unsuitable for participation in this clinical study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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No. 197 Ruijin 2nd road, Huangpu District
Shanghai, Shanghai Municipality, 200020, China
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