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New Low-Dose CT protocol aims to slash radiation in kids

NCT ID NCT07199101

Knowledge-focused Sponsor: Beijing Children's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will develop and test a low-dose CT scanning protocol specifically for children, who are more sensitive to radiation. Researchers will use simulation technology to create the protocol and then verify it in a large trial with 2,650 children across multiple hospitals. The goal is to reduce radiation exposure while maintaining image quality needed for accurate diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Low-dose CT scan
What this could lead to
If successful, this could establish a safer, widely usable CT protocol for children, reducing radiation exposure without sacrificing diagnostic accuracy.
What could go wrong
This is an early-stage protocol development study, not testing a new drug or cure. The low-dose images might not be clear enough for all diagnoses, and results may vary across hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 2,650 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

0 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 0-17 years. * Pediatric patients for whom a CT examination is deemed necessary by an attending physician. Exclusion Criteria: * Parents/guardians refuse to consent to low-dose CT examination. * Pediatric patients are in critical condition, with no time allocated for explanation of the randomized controlled trial (RCT) protocol.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Radiation dose reduction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    20 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Affiliated Women's Hospital of Jiangnan University

    Wuxi, Jiangsu, China

  • Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical University

    Baoding, Heibei, China

  • Beijing Children's Hospital, Capital Medical University, National Center for Children's Health

    Beijing, Beijing Municipality, China

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Beijing Municipality, China

  • Beijing Tongren Hospital, Capital Medical University

    Beijing, Beijing Municipality, China

  • Children's Hospital of Changchun

    Changchun, Jilin, China

  • Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders.

    Chongqing, Chongqing Municipality, China

  • Fuwai Central China Cardiovascular Hospital

    Zhengzhou, Henan, China

  • Guangdong Women and Children Hospital

    Guangzhou, Guangdong, China

  • Medical Center for Capital Children's Health, Capital Medical University

    Beijing, Beijing Municipality, China

  • Nanfang Hospital, Southern Medical University

    Guangzhou, Guangdong, China

  • National Institute for Radiological Protection, China CDC

    Beijing, Beijing Municipality, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, China

  • People's Hospital of Xinjiang Uygur Autonomous Region

    Ürümqi, Xinjiang, China

  • Shanghai Children's Medical Center, School of Medicine

    Shanghai, Shanghai Municipality, China

  • Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, China

  • ShanghaiTech University

    Shanghai, Shanghai Municipality, China

  • The First Affiliated Hospital of Xi'an Jiao Tong University

    Xi'an, Shaanxi, China

  • The Third Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, China

  • the First Hospital of Jilin University

    Changchun, Jilin, China