Trikafta passes long-term safety check in toddlers with cystic fibrosis
NCT ID NCT05153317
First seen Mar 15, 2026 · Last updated May 22, 2026 · Updated 12 times
Summary
This study looked at the long-term safety and effectiveness of the triple-combination drug Trikafta (elexacaftor/tezacaftor/ivacaftor) in 71 children aged 2 and older with cystic fibrosis. All participants had already taken the drug in an earlier study. The main goal was to track side effects, and secondary goals included changes in sweat chloride and lung function. Because cystic fibrosis requires lifelong medication, this treatment controls the disease but is not a cure.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CYSTIC FIBROSIS are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Alder Hey Children's NHS Foundation Trust
Liverpool, United Kingdom
-
Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
-
Banner University of Arizona Medical Center
Tucson, Arizona, 85724, United States
-
Boston Children's Hospital
Boston, Massachusetts, 02115, United States
-
British Columbia Children's Hospital
Vancouver, Canada
-
Charite Paediatric Pulmonology Department
Berlin, Germany
-
Children's Hospital of Colorado
Aurora, Colorado, 80045, United States
-
Children's Respiratory and Critical Care Specialists, P.A., Children's Hospitals and Clinics of Minnesota
Minneapolis, Minnesota, 55404, United States
-
NC TraCS Institute - CTRC University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
-
Oregon Health & Science University
Portland, Oregon, 97239, United States
-
Queensland Children's Hospital
South Brisbane, Australia
-
Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, 46202, United States
-
Royal Brompton Hospital
London, United Kingdom
-
Seattle Children's Hospital
Seattle, Washington, 98105, United States
-
Stanford University
Palo Alto, California, 94304, United States
-
Telethon Kids Institute
Nedlands, Australia
-
The Children's Mercy Hospital
Kansas City, Missouri, 64108, United States
-
The Hospital for Sick Children
Toronto, Canada
-
The Royal Children's Hospital
Parkville, Australia
-
UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
-
Universitatsklinikum Essen (AoR), Kinderklinik III, Abt. fur Pneumologie
Essen, Germany
-
Washington University School of Medicine / St. Louis Children's Hospital
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.