15-Year watch begins for CAR T-Cell therapy recipients
NCT ID NCT06652633
First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times
Summary
This study follows about 546 people who have already received a Galapagos CAR T-cell therapy for blood cancers. Researchers will check for long-term side effects and how well the treatment works over 15 years. No new treatment is given—just regular monitoring to meet safety guidelines for gene therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 546 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Jul 2039
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All participants who have been treated with a Galapagos CAR T-cell therapy in a clinical trial or Managed Access Program. Exclusion Criteria: * There are no exclusion criteria for this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
11 sites in 5 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Academisch Medisch Centrum (Amsterdam UMC)
RECRUITINGAmsterdam, 1105 AZ, Netherlands
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Algemeen Ziekenhuis Delta
RECRUITINGRoeselare, 8800, Belgium
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Antwerp University Hospital
RECRUITINGEdegem, 2650, Belgium
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Centre Hospitalier Universitaire (CHU) De Liège
RECRUITINGLiège, 4032, Belgium
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Cliniques Universitaires Saint-Luc
RECRUITINGWoluwe-Saint-Lambert, 1200, Belgium
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Erasmus Medisch Centrum
RECRUITINGRotterdam, 3015, Netherlands
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Hospital Clinic De Barcelona
RECRUITINGBarcelona, 08036, Spain
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Leids University Medical Center (LUMC)
RECRUITINGLeiden, 2333 ZA, Netherlands
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Tufts Medical Center
RECRUITINGBoston, Massachusetts, 02111, United States
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Universitair Ziekenhuis Leuven
RECRUITINGLeuven, 3000, Belgium
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helsingin yliopistollinen sairaala comprehensive cancer center (HUS)
RECRUITINGHelsinki, 00290, Finland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Softer chemo before stem cell transplant aims to save more blood cancer patients
- Can a Nine-Week group program help blood cancer patients grow through trauma?
- Off-the-Shelf CAR-T cells target CD70 in Hard-to-Treat blood cancers
- Off-the-Shelf CAR-T cells target a marker on stubborn blood cancers
- Can a simple blood test outsmart deadly fungal infections in blood cancer?
- Can a gentler chemo prep make stem cell transplants safer for blood cancer patients?