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Gene therapy watch: 5-Year Follow-Up for rare brain diseases begins

NCT ID NCT06614569

First seen Oct 31, 2025 · Last updated May 19, 2026 · Updated 27 times

Summary

This study checks on 7 people with Tay-Sachs or Sandhoff disease who received a gene therapy called AXO-AAV-GM2. Researchers will watch for side effects and see how the treatment affects their thinking, movement, and daily life over 5 years. The goal is to learn if the therapy is safe and helps control these serious genetic conditions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UMass Chan Medical School

    Worcester, Massachusetts, 01655, United States

Conditions

Explore the condition pages connected to this study.