Blood bank mystery: does old blood raise death risk in trauma?
NCT ID NCT07341139
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study looks at whether storing blood for a long time before transfusion affects death rates and complications in severely injured trauma patients. Researchers will review records of 300 patients aged 18-75 who received large transfusions. The goal is to understand if blood storage time is linked to higher mortality or health problems like heart issues or infections.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If this study finds a link, it could lead to safer blood storage practices and better outcomes for trauma patients.
- What could go wrong
- This is an observational study, not a treatment trial, so it cannot prove cause and effect. Results may be influenced by other factors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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101 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Jun 2026
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
In our study, patients between the ages of 18-75, directly from the scene of injury, ISS\>15 and who received massive blood transfusion (\>10 packed RBC units in the first 24 hours, with an alternative definition of greater than or equal to 3 packed RBC units transfused in 1 hour) will be included in the study at University of Florida Jacksonville Shands Hospital between the dates 1 January 2023 to 1 31 December 2025.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients between 18-75 years of age, * Injury Severity Score\>15 and have received massive blood transfusions in our hospital from 1 January 2015 to 31 December 2025 * The patients admitted because of trauma and undergoing surgery Exclusion Criteria: * Patients with known cardiac or vascular diseases such as heart failure or malignant hypertension, those under anticoagulant treatment * Patients with known serious kidney (on dialysis), lung, liver diseases, those under anticoagulant treatment * Super obese patients with body mass index (BMI) 50 or above
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UF Health Jacksonville (Shands Hospital)
Jacksonville, Florida, 32209, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.