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Skin biopsies may reveal long COVID's hidden nerve damage

NCT ID NCT07005947

Knowledge-focused Sponsor: CND Life Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study looks at tiny nerve fibers in the skin of people with Long COVID, POTS, diabetic neuropathy, and those who had COVID-19 without lasting symptoms. By comparing skin samples, researchers hope to find unique patterns that help explain ongoing symptoms like pain and dizziness. The goal is to better understand these conditions, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

237 people

The number who actually took part.

Started

Nov 2023

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Male and females ages 18-80 who have been diagnosed with one of the following: 1\. Long COVID defined by NIH PASC criteria OR 2. Acute COVID who tested positive for COVID without persistent symptoms OR 3. Postural orthostatic tachycardia syndrome (POTS) OR 4. Diabetic neuropathy

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria, just one of the following: * Long COVID-19 defined by NIH PASC criteria OR * Acute COVID-19 who tested positive for COVID-19 without persistent symptoms OR * Postural orthostatic tachycardia syndrome (POTS) OR * Diabetic neuropathy Exclusion Criteria: * Clinical evidence of severe peripheral vascular disease * History of ulceration, poor wound healing or vascular claudication * History of allergic reaction to local anesthesia (for biopsy collection) * Use of oral anticoagulants (aspirin or Plavix alone is allowed) * History of a bleeding disorder

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Conditions

The condition(s) this trial relates to.

COVID-19 diabetic neuropathy long COVID-19 postural orthostatic tachycardia syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute COVID-19 Diabetic neuropathy Long COVID-19 Postural orthostatic tachycardia syndrome (POTS)

Contacts and locations

Locations

  • CND Life Sciences

    Scottsdale, Arizona, 85258, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.