Brain's attention hub revealed in new study
NCT ID NCT06041048
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at a small part of the brain called the locus coeruleus, which helps control attention. Researchers will use special MRI scans to measure its activity in 40 healthy adults. The goal is to better understand how this area works, which may help with conditions like ADHD in the future.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Between the ages of 18 - 60 years of age, * Typically developing, healthy adult Exclusion Criteria: * History of schizophrenia, other forms of psychosis, * Specific or focal neurological disorder or severe alcohol or drug use disorder within the past 5 years * History of left ventricular hypertrophy or in patients with mitral valve prolapse who have experienced the mitral valve prolapse syndrome when previously receiving CNS stimulants, or who have had recent history of myocardial infarction or unstable angina. * Volunteers with known hypersensitivity to modafinil or armodafinil or its inactive ingredients * Known allergy/sensitivity or any hypersensitivity to components of modafinil or its formulation * Inability to swallow tablets or tolerate oral medication; * Pregnant or nursing (participants will be required to have a negative pregnancy test) * Contraindication for MRI scanning (metal implants, pacemakers, metal foreign bodies, or pregnancy) * Use of psychotropic medication within the past week * Claustrophobic and not comfortable being in a small space may also not want to participate
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of California, Davis
RECRUITINGSacramento, California, 95817, United States