Gene hunt in lobular breast cancer could personalize care
NCT ID NCT05410951
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 800 people with a type of breast cancer called lobular breast cancer. Researchers are searching for inherited gene changes that may raise cancer risk. Depending on the gene found, patients may get closer monitoring or preventive surgery. The goal is to tailor follow-up care based on each person's genetic results.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 800 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2022
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with in situ (LIN3) or invasive LBC or bilateral LBC or LBC with or without family history for BC, with blood sample available in European Institute of Oncology biobank
- Ages
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18 to 99 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: 1. All LBC observed retrospectively at the European Institute of Oncology, with a proved diagnosis of LBC (biopsy or operated) 2. Patients with blood available in biobank Exclusion criteria * Patients with a previous cancer (except skin basal cell carcinoma) * Patients with ductal or mixed BC
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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European Institute of Oncology
Milan, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Two-Drug combo shrink BRCA-Linked breast tumors?
- New PET tracer aims to spot hidden cancer spread in the abdomen
- Could a scan replace surgery for breast cancer staging?
- New study aims to spot hidden cancer spread in lobular breast cancer
- Scientists investigate rare breast cancer subtype to improve future care