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Early safety check: how a damaged liver handles an experimental drug

NCT ID NCT07049939

Summary

This early-stage study aimed to understand how a drug called bomedemstat (MK-3543) behaves in people with mild or moderate liver impairment. Researchers gave a single dose to 9 participants—some with liver problems and some healthy—and tracked the drug levels in their blood over time. The goal was to see if liver damage changes how the body processes the drug, which is important for future dosing and safety.

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Contacts and locations

Locations

  • Orlando Clinical Research Center ( Site 0001)

    Orlando, Florida, 32809, United States

  • The Texas Liver Institute ( Site 0002)

    San Antonio, Texas, 78215, United States

  • University of Miami ( Site 0003)

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.