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Can ultrasound replace MRI for fatty liver diagnosis?

NCT ID NCT07373769

Knowledge-focused Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether a special ultrasound technique can measure liver stiffness and fat as accurately as MRI in people with fatty liver disease. Researchers will compare results from both imaging methods in 145 healthy volunteers and patients. The goal is to find a simpler, more affordable way to diagnose and monitor liver disease without invasive biopsies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a cheaper, more accessible ultrasound-based alternative to MRI for diagnosing fatty liver disease.
What could go wrong
This is an early imaging comparison study, not a treatment trial. It may not show that ultrasound is accurate enough to replace MRI or biopsy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 145 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Jul 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy volunteers from the University of British Columbia and gastroenterology patients with chronic liver disease from the Vancouver General Hospital or from the St. Paul's hospital, both from Vancouver, British Columbia.

Ages

19 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants between the ages of 19 and 75. * healthy volunteers and have no known history of liver disease * patients with chronic liver disease, with fibrosis stages F0, F1, F2, F3 or F4. Exclusion Criteria: Does not speak and/or read English CANNOT undergo an MRI exam for one of the following reasons: * Retained wires from an electronic implant that has been removed (i.e. pacemaker wires not attached to a pacemaker) * Cardiac pacemaker or defibrillator * Metal in eye or orbit * Ferromagnetic aneurysm clip * Pregnancy * Makeup tattoos that are not designed to fade over time * Stainless steel intrauterine device (IUD) Depending on the individual situation, patients MAY NOT be able to participate the MRI exam if they have/had any of the following: * Artificial heart valve * Ear or eye implant * Brain aneurysm clip * Implanted electronic device (i.e. drug infusion pump, electrical stimulator) * Coil, catheter, or filter in any blood vessel * Orthopedic hardware (artificial joint, plate, screw, rod) * Shrapnel, bullets, or other metal fragments * Surgery, medical procedure or tattoos (including tattooed eyeliner) in the last six weeks * Other metallic prostheses

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Conditions

The condition(s) this trial relates to.

fatty liver disease Fibrosis Inflammation metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Metabolic dysfunction-associated steatotic liver disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of British Columbia

    Vancouver, British Columbia, V6T1Z4, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.