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New combo therapy aims to shrink liver tumors after other treatments fail

NCT ID NCT03259867

First seen Apr 18, 2026 · Last updated May 22, 2026 · Updated 4 times

Summary

This study tests a two-step treatment for people with advanced liver cancer or stomach cancer that has spread to the liver. First, a drug called tirapazamine is injected directly into the liver's blood vessels to block and kill tumor cells. Then, patients receive nivolumab, an immunotherapy that helps the immune system attack cancer. The goal is to see if this combination can shrink tumors in patients whose cancer worsened after prior immunotherapy. About 54 adults aged 18 to 80 will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Email: •••••@•••••

  • University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Email: •••••@•••••

    Contact

    Contact

  • University of Oklahoma Health Science Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.