New hope for advanced liver cancer patients in major global trial

NCT ID NCT04194775

Ongoing Disease control Sponsor: CStone Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This large Phase 3 study is testing whether adding a new immunotherapy drug (nofazinlimab) to an existing cancer drug (lenvatinib) works better than lenvatinib alone for people with advanced liver cancer that can't be removed by surgery. The trial involves 534 patients who haven't received any prior systemic cancer treatment. Researchers will compare how long patients live and how well the cancer responds between the two treatment groups.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Affiliated Hospital Of Jining Medical University

Jining, Shandong, China
Azienda Unità Locale Socio Sanitaria n. 1 Dolomiti, Distretto di Feltre, Ospedale di Feltre

Feltre, Belluno, Italy
Beijing Cancer Hospital

Beijing, Beijing Municipality, China
Beijing You'an Hospital, Capital Medical University

Beijing, Beijing Municipality, China
Casa di Cura Dott. Pederzoli S.p.A (Ospedale Pederzoli)

Peschiera del Garda, Verona, Italy
Centrum Badan Klinicznych

Wroclaw, Lower Silesian Voivodeship, Poland
Centrum Onkologii im. prof. F. Lukaszczyka

Bydgoszcz, Poland
Chi Mei Hospital, Liouying - Department of Oncology

Tainan, Taiwan
Chi Mei Medical Center - YongKang - Gastroenterology - Gastroenterology

Tainan, Taiwan
China Medical University Hospital - Internal Medicine - Taichung

Taichung, Taiwan
Complejo Hospitalario Universitario de Orense

Ourense, Galicia, Spain
Complexo Hospitalario Universitario A Coruña

A Coruña, Galicia, Spain
Consorcio Hospital General Universitario de Valencia

Valencia, Spain
Fondazione IRCCS Policlinico San Matteo

Pavia, Italy
Foshan First People's Hospital

Foshan, Guangdong, China
Guangxi Medical University Affiliated Tumor Hospital

Nanning, Guangxi, China
H.U. de Burgos

Burgos, Spain
H.U.V.Arrixaca

Murcia, Spain
Hainan General Hospital - Hepatology

Haikou, Hainan, China
Harbin Medical University Cancer Hospital

Harbin, Heilongjiang, China
Henan Cancer Hospital

Zhengzhou, Henan, China
Hospital Del Mar

Barcelona, Spain
Hospital General Universitario Gregorio Marañón

Madrid, Spain
Hospital Ntra. Sra. de Sonsoles

Ávila, Spain
Hospital Universitario Central de Asturias

Oviedo, Principality of Asturias, Spain
Hospital Universitario La Paz

Madrid, Spain
Hospital Universitario Puerta De Hierro De Majadahonda

Majadahonda, Madrid, Spain
Hospital Universitario Virgen De La Macarena

Seville, Spain
Hospital Unviersitario Miguel Servet

Zaragoza, Spain
Hunan Cancer Hospital - Radiology

Changsha, Hunan, China
Hunan Provincial People's Hospital

Changsha, Hunan, China
ICO-Hospital Universitari de Girona Dr. Josep Trueta

Girona, Spain
Inland Empire Liver Foundation

Rialto, California, 92377, United States
Istituto Oncologico Veneto IOV IRCCS - Medical Oncology Unit 1

Padua, Veneto, Italy
Jinan Military Region General Hospital of the People's Liber

Jinan, Shandong, China
Linyi Cancer Hospital

Linyi, Shandong, China
Luoyang Central Hospital

Luoyang, Henan, China
MED-POLONIA Sp.z o.o.

Poznan, Greater Poland Voivodeship, Poland
Mercy Medical Center

Baltimore, Maryland, 21202, United States
Nanfang Hospital

Guangzhou, Guangdong, China
Nantong Tumor Hospital

Nantong, Jiangsu, China
Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

Warsaw, Poland
National Cheng Kung University Hospital - Internal Medicine

Tainan, Taiwan
PO di Cremona, ASST di Cremona - Oncologia - Cremona - Radiology

Cremona, Italy
Peking Union Medical College Hospital

Beijing, Beijing Municipality, China
Shangdong Provicial Qianfoshan Hospital

Jinan, Shandong, China
Shanghai Cancer Hospital of Fudan University

Shanghai, Shanghai Municipality, China
Shanghai Eastern Hepatobiliary Surgery Hospital - Hepatology

Shanghai, Shanghai Municipality, China
Shanghai First People's Hospital

Shanghai, Shanghai Municipality, China
Sichuan University - West China Hospital

Chengdu, Sichuan, China
Southern California Research Center

Coronado, California, 92118, United States
Stony Brook University Cancer Clinical Trials

Stony Brook, New York, 11794, United States
Taichung Veterans General Hospital - Gastroenterology

Taichung, Taiwan
The 900th Hospital of Joint Logistic Support Force of PLA

Fuzhou, Fujian, China
The Affiliated Hospital of Qingdao University

Qingdao, Shandong, China
The First Affiliated Hospital Of Anhui Medical University

Hefei, Anhui, China
The First Affiliated Hospital of Bengbu Medical College

Bengbu, Anhui, China
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine

Guangzhou, Guangdong, China
The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China
The First People's Hospital of Huai'an

Huai'an, Jiangsu, China
The Second Affiliated Hospital of Anhui Medical University

Hefei, Anhui, China
The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China
The Second Affiliated Hospital of Soochow University

Suzhou, Jiangsu, China
The Third Xiangya Hospital of Central South University

Changsha, Hunan, China
Tianjin Medical University - Cancer Institute & Hospital - Oncology

Tianjin, Tianjin Municipality, China
Tongji Hospital - Medical Oncology

Wuhan, Hubei, China
Tri-Service General Hospital - Neihu Branch - Pulmonary

Taipei, Taiwan
UMass Memorial Medical Center

Worcester, Massachusetts, 01655, United States
Xuzhou Central Hospital

Xuzhou, Jiangsu, China
Yanbian University Hospital

Yanbian, Jilin, China
Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China
Zhengzhou University - First Affiliated Hospital

Zhengzhou, Henan, China
Zhongshan Hospital, Fudan University

Shanghai, Shanghai Municipality, 201203, China
hubei Cancer Hospital

Wuhan, Hubei, China

Conditions

Explore the condition pages connected to this study.

HEPATOCELLULAR CARCINOMA