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Fat emulsion may reverse spinal numbing faster after surgery

NCT ID NCT06988982

Symptom relief Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This trial investigates whether a fatty liquid given through a vein can help reverse the effects of spinal anesthesia more quickly after same-day surgery. The study includes 70 adults aged 21–70 undergoing elective procedures like general, urology, gynecology, or orthopedic surgery. Participants receive either the lipid emulsion or a placebo, and researchers measure how fast sensation and movement return.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Intravenous Lipid Emulsion 20%
What this could lead to
If effective, this could offer a way to reverse spinal anesthesia more quickly, reducing recovery time and hospital stay for same-day surgery patients.
What could go wrong
This is a small, early-stage trial with 70 participants, so results may not apply broadly. The lipid emulsion may not speed recovery or could cause side effects like allergic reactions or fat overload.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

Jun 2025

Finished

Feb 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient acceptance. * Cooperative patient * Age 21-70 years old. * BMI ≤ 35 kg/m2 * ASA I - II. * Elective ambulatory surgery under spinal anesthesia (general surgery, urology, gynecology, orthopedic surgery). Exclusion Criteria: * History of allergy to the LA agents used in this study, * Skin lesion at needle insertion site, * Those with bleeding disorders, sepsis, liver disease and psychiatric disorders * History of cognitive dysfunction or mental illness

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ambulatory surgery Spinal anaesthesia Spinal anesthesia evaluation

Contacts and locations

Locations

  • Zagazig University Hospitals

    Zagazig, Al Sharqia, 44519, Egypt

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