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New biorepository aims to unlock secrets of lipedema

NCT ID NCT06180850

Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study created a biorepository of blood and tissue samples from 60 women with and without lipedema. The goal was to find molecular markers that can distinguish lipedema from obesity, which is often misdiagnosed. Researchers measured immune markers and physical function tests to better understand the disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better diagnostic tools for lipedema, helping distinguish it from obesity and enabling earlier management.
What could go wrong
This is an observational study that does not test a treatment, so it will not directly help patients. Results may not lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Feb 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants with or without lipedema

Ages

18 to 80 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants with or without lipedema * Age range = 18-80 years * Participants with lipedema have a formal diagnosis by a physician using criteria in Appendix A of protocol * Female Exclusion Criteria: Volunteers in the lipedema or control group will be excluded with the following: * Pregnant or breast-feeding * Taking any anticoagulation or antiplatelet therapy other than aspirin (up to 100 mg daily) * Active infection anywhere in the body, or open wound on the lower-extremities or at locations for ultrasound, bioimpedance, and tissue dielectric measurements * Battery-operated device implanted that cannot be removed for ultrasound, DXA scan, bioimpedance, and tissue dielectric measurements * Primary lymphedema * Uncontrolled diabetes, renal disease, thyroid disease, or hypertension * Hormone dysregulation or another significant clinical condition affecting hormone status as confirmed by clinical co-investigators * Bone metastases * Contrast imaging scan in the previous 7 days * Nuclear medicine scan in previous 3 days * Lumbar spine fusion * Weigh more than 500 lb (226.8 kg) Also excluded are subjects incapable of giving informed written consent: * Subjects who have an inability to communicate with the researcher for any reason * Subjects who are non-English speaking who cannot communicate through a translator, or if a translator is not available * Subjects who cannot adhere to the experimental protocols for any reason * Subjects who have limited mental ability to give informed consent due to mental disability, confusion, or psychiatric disorders * Prisoners

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Conditions

The condition(s) this trial relates to.

Lipedema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lipedema

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37203, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.