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New ultrasound test could spot painful fat disorder often mistaken for obesity

NCT ID NCT07536646

Diagnosis Sponsor: Fatih Sultan Mehmet Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether shear wave elastography, a special ultrasound technique that measures tissue stiffness, can help diagnose lipedema—a chronic condition causing painful fat buildup in the legs, mostly in women. Researchers compared tissue stiffness in 95 women (lipedema patients vs. healthy controls) at four leg and abdomen sites. The goal is to find a reliable, noninvasive way to distinguish lipedema from similar conditions like obesity or lymphedema.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Shear wave elastography (ultrasound-based tissue stiffness measurement)
What this could lead to
If successful, this could provide a new, noninvasive way to diagnose lipedema more accurately and distinguish it from similar conditions like obesity or lymphedema.
What could go wrong
This is a small, completed study (95 participants) comparing tissue stiffness, not a treatment trial. The technique may not prove reliable enough for routine clinical use without larger validation studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

95 people

The number who actually took part.

Started

Jan 2026

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Women aged ≥18 years with lipedema (stages 1-3) and healthy controls were included.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged ≥18 years with lipedema (stages 1-3) and healthy controls with adequate cognitive function Exclusion Criteria: * Age \<18 years Lymphedema Edema of cardiac or nephrogenic origin Diabetes mellitus Thyroid dysfunction Oncological diseases Polyneuropathy or radiculopathy Advanced degenerative diseases affecting the extremities Use of antiepileptic or antidepressant drugs within the last 6 months Use of edema-inducing medications (e.g., corticosteroids, calcium channel blockers, gabapentin, pregabalin) Cognitive impairment preventing participation

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Conditions

The condition(s) this trial relates to.

Lipedema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lipedema

Contacts and locations

Locations

  • Fatih Sultan Mehmet Education and Training Hospital

    Istanbul, Ataşehir, 34752, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.