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New hope for lung cancer that morphs after treatment

NCT ID NCT07001995

First seen Mar 26, 2026 · Last updated Jun 22, 2026 · Updated 9 times

Summary

This study tests a combination of the drug limertinib plus chemotherapy (etoposide and carboplatin) in 30 people with a specific type of lung cancer. These patients have a gene mutation (EGFR) and their cancer has changed from non-small cell to small cell lung cancer after previous treatment. The goal is to see if the combo can slow cancer growth and shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yongchang Zhang

    Changsha, Hunan, 410013, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

limertinib combined with etoposide and carboplatin

What this could lead to

If this works, it could offer a new treatment option for patients whose lung cancer changes form after standard therapy.

What could go wrong

This is a small, early-phase study with only 30 participants, so results may not apply widely. The combination may cause significant side effects.

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.