Wearable tech tracks movement in rare bone disorders
NCT ID NCT07388966
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for people aged 3 and older with achondroplasia or hypochondroplasia (types of skeletal dysplasia). It uses a wearable device called Syde® to measure limb movements over a year. The goal is to find out which movement measurements are reliable and useful for future research. No treatment is given—this is an observational study to better understand the condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Feb 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants will be recruited from the patient registry of the Centre de Référence des Maladies Osseuses Constitutionnelles located at NeckerHospital / IMAGINE Institute. The APPT association (Association des Personnes de Petite Taille) will also help with the recruitment through flyers distribution. All visits will take place at Necker Hospital.
- Ages
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3 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Aged 3 years old or older at the time of consent. 2. Written informed consent obtained: 1. From the parent(s) or legal guardian(s) for participants under 18 years old. 2. From participants 18 years old and older. 3. Affiliated to, or beneficiary of a social security category 4. Able to walk unassisted for at least 10 meters. 5. Genetically confirmed diagnosis with one pathogenic variant (ACMG class IV \& V) of achondroplasia or hypochondroplasia. 6. Participant (and caregivers for participants under 18 years old) willing and able to comply with all study procedures including: questionnaires, Syde® related procedures Exclusion Criteria: 1. Subjects who have short stature condition other than ACH/HCH. 2. Presence of cognitive disorders that limit their understanding of the data collection process (training of device use and 4-week recording periods every 6 months, device return at the end of the study), the implication of the study and consent. 3. Presence or history of any concurrent disease or condition that could interfere with study participation, impact pediatric growth, affect motor or balance or gait function (such as neurological, endocrine, infectious, allergic, osteoarthritis, or inflammatory), assessed by the investigator. 4. Females who are pregnant, or planning to become pregnant during the study duration. 5. Body Mass Index = 35 kg/m2. 6. Recent upper and/or lower limbs injury (trauma/fracture or surgery) in the 6 months preceding inclusion. 7. Prior limb lengthening surgery or planned or expected to have limb lengthening surgery while enrolled in the study. 8. Presence of guided growth hardware (such as 8-plates) or planned orthopedic surgeries during the study. 9. Vulnerable patient (guardianship, curatorship or safeguarding of justice), unable to provide informed consent or who is unable to express their consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hopital Necker
RECRUITINGParis, 75015, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Daily Bone-Growth drug tested for taller stature in hypochondroplasia
- Can a weekly shot help children with achondroplasia grow taller?
- Can growth hormone boost height in children with dwarfism?
- Weekly shot may boost growth in kids with dwarfism
- Experimental achondroplasia drug trial halted early
- No treatment, just tracking: PROPEL study watches how kids with achondroplasia grow