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Light therapy for depression: does season matter?

NCT ID NCT07599124

Symptom relief Sponsor: Geestelijke Gezondheidszorg Eindhoven (GGzE) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether bright light therapy helps depression equally well in spring/summer compared to autumn/winter. Over 200 adults with depression received daily 30-minute light sessions for at least a week. Researchers measured symptom changes and followed up for three months to see if the season affects how well the treatment works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Bright light therapy (10,000 lux LED lamp)
What this could lead to
If successful, this could show that light therapy works year-round for depression, not just in darker seasons.
What could go wrong
This is a completed observational study, not a large controlled trial. Results may not apply to all types of depression, and individual responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

212 people

The number who actually took part.

Started

Jan 2021

Finished

Dec 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of patients with depression who are referred for treatment of depressive symptoms within a mental health care setting (GGzE, Eindhoven, The Netherlands), where bright light therapy is offered in a structured "Light Café" environment as part of routine clinical care.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Diagnosis of a depressive disorder (unipolar or bipolar), including both seasonal and non-seasonal depression * Currently indicated for bright light therapy * QIDS-SR score ≥ 6 at baseline * Able to provide informed consent * Sufficient proficiency in Dutch or English to complete questionnaires Exclusion Criteria: * Current (hypo)manic or mixed episode * Current psychotic episode * Severe suicidal ideation requiring immediate intervention * Diagnosis of dementia * QIDS-SR score ≤ 5 at baseline * Age \< 18 years * Inability to provide informed consent * Insufficient language proficiency to complete study questionnaires * Initiation, dose change, or switch of antidepressant medication within 3 weeks before or during light therapy * Long-term use of agomelatine Relative Contraindications (require consultation with treating physician before participation): * Pregnancy (first trimester) * Diabetes or other systemic vascular diseases * Eye conditions associated with increased light sensitivity * Epilepsy Medication-Related Considerations: * Participants are advised not to start antibiotics during light therapy (existing courses should be completed prior to participation) * Participants are advised to discontinue use of photosensitizing medications or topical agents during treatment * Participants are asked to discontinue melatonin use during light therapy * A wash-out period of 1 month is required after discontinuation of melatonin or short-term agomelatine use before starting light therapy

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Conditions

The condition(s) this trial relates to.

bipolar depression Depression depressive disorder endogenous depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bipolar depression depressed phase Depression Unipolar depression

Contacts and locations

Locations

  • GGzE

    Eindhoven, 5626ND, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.