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New surgical tool may protect voice box during thyroid surgery

NCT ID NCT07522983

Disease control Sponsor: Gulab Devi Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two ways to control bleeding during total thyroidectomy: using a device called LigaSure versus traditional knot tying. Researchers looked at whether LigaSure caused fewer injuries to the nerve that controls the voice box. The study involved 120 patients aged 18 to 60 with no prior neck surgery or voice issues.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
LigaSure device
What this could lead to
If LigaSure proves safer, it could become the preferred method for thyroid surgery, reducing voice complications.
What could go wrong
This is a small, single-center study. Results may not apply to all patients or surgeons, and the device may not significantly reduce injury risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Jul 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged: 18 to 60 years * Both Gender * Patients undergoing total thyroidectomy * Normal IDL * No Hoarseness of voice Exclusion Criteria: * Patients requiring re-operation, including completion thyroidectomy. * Patients undergoing concurrent procedures such as cervical lymphadenectomy or parathyroidectomy. * Patient having previous neck surgery * Patient having neck radiation * Thyroidectomy for thyroid malignancy

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Conditions

The condition(s) this trial relates to.

thyroid gland disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Thyroidectomy

Contacts and locations

Locations

  • Gulab Devi Hospital Ferozpur Road Lahore

    Lahore, Punjab Province, 54600, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.