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Could a chemo drug unlock language in kids with autism?

NCT ID NCT02839915

First seen May 11, 2026 · Last updated May 22, 2026 · Updated 3 times

Summary

This study tests whether folinic acid (leucovorin), a drug already used to reduce side effects from chemotherapy, can improve language skills in children with autism spectrum disorder. About 56 children aged 5 to 17 will take the drug for 12 to 24 weeks. Researchers will measure changes in language tests and overall improvement. The goal is to see if this treatment can ease language problems, not cure autism.

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Contacts and locations

Locations

  • Children's Healtcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • Harvard University

    Lexington, Massachusetts, 02421, United States

  • Southwestern Research and Resource Center

    Phoenix, Arizona, 85016, United States

  • State University of New York, Downstate

    Brooklyn, New York, 11203, United States

Conditions

Explore the condition pages connected to this study.