Women's protein needs may change with their cycle, tiny study suggests
NCT ID NCT06533501
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether the amount of leucine (a key protein building block) women need changes during different phases of the menstrual cycle. Thirteen women with regular cycles ate controlled meals and gave breath and urine samples. The goal is to see if current one-size-fits-all protein guidelines for women need updating.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dietary leucine
- What this could lead to
- If successful, this could help set more accurate dietary protein recommendations for women, tailored to their menstrual cycle.
- What could go wrong
- This is a very small, early-stage study (13 participants) that only measures a metabolic marker, not health outcomes. Results may not apply to all women.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
13 people
The number who actually took part.
- Started
-
Mar 2024
- Finished
-
Jun 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 to 35 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * People with menstrual cycles * Between the ages of 20 to 35y * Regular menstrual cycle (21-35 day cycle) for the past 12 months * Body mass index (BMI) of between 18 and 28 kg/m2 * Free from pre-existing health conditions Exclusion Criteria: * People who are currently using hormonal birth control or any contraceptive that would affect sex hormones * People on hormone therapy * People with an abnormal menstrual cycle history * People with non-traditional dietary practices * Recent weight loss/weight gain * People with a history of endocrine disorders * People who are pregnant * People who are breastfeeding * People who have given birth in the last 18 months * People who depend on medication that affects normal metabolism. Any medication that alters normal body metabolism would skew the results and compromise the validity of the data set. * People with a metabolic, neurological, genetic, or immune disorder likely to affect nutritional requirements or overall body metabolism.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
BC Children's Hospital Research Institute
Vancouver, British Columbia, V5Z 4H4, Canada
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