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New combo aims to supercharge immune system against blood cancer

NCT ID NCT01351896

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 33 times

Summary

This study tests whether combining the drug lenalidomide with a vaccine can help people with early-stage chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have high-risk genetic features. Lenalidomide aims to boost the immune system and stop cancer growth, while the vaccine trains the body to better attack cancer cells. The main goal is to see if this combination improves antibody responses against infections.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia chronic lymphocytic leukemia/small lymphocytic lymphoma pregerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.