New knee implant put to the test: will it last 10 years?
NCT ID NCT07199738
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 35 times
Summary
This study is testing the LEGION Medial Stabilized knee implant in 144 people who need total knee replacement due to arthritis or joint damage. The main goal is to see how long the implant lasts without needing revision surgery, with follow-up over 10 years. Different versions of the implant (cemented or cementless) will be used to compare safety and performance.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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New York University Hospital
New York, New York, 10016, United States
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Newton Wellesley Hospital
Newton, Massachusetts, 02462, United States
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Rothman Orthopedics-Advent Health
Orlando, Florida, 32803, United States
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The Core Institute
Phoenix, Arizona, 85023, United States
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University of Wisconsin
Madison, Wisconsin, 53715-1218, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LEGION Medial Stabilized knee implant (with cemented or cementless components)
What this could lead to
If successful, this could confirm that the LEGION knee implant is safe and lasts at least 10 years for most patients, supporting its continued use in knee replacement surgery.
What could go wrong
This is a relatively small study (144 people) and results may not apply to everyone. Implants can fail or cause complications, and long-term follow-up is needed to see if it truly lasts.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.