New drug targets eczema itch even when rash is mild
NCT ID NCT07006792
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 37 times
Summary
This study tests whether lebrikizumab can reduce itching and skin symptoms in people with moderate eczema who have a high itch burden. About 233 adults and teens will receive the drug for 24 weeks. The main goal is to see if at least 75% of skin symptoms improve or if itch scores drop by at least 4 points.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Albuquerque Clinical Trials, Inc.
Albuquerque, New Mexico, 87102, United States
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AlergoAlpha - Barueri
Barueri, 06454-010, Brazil
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Allergy & Asthma Specialists, P.S.C.
Owensboro, Kentucky, 42301, United States
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Alliance Dermatology and Mohs Center
Phoenix, Arizona, 85032, United States
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Biopharma Informatic, LLC
Houston, Texas, 77084, United States
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Brunswick Dermatology Center
Fredericton, E3B 1G9, Canada
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CEPIC - Centro Paulista de Investigação Clínica
São Paulo, 04266-010, Brazil
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CIPREC
Buenos Aires, 1061, Argentina
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CMRC Headlands, LLC
San Juan, 00918, Puerto Rico
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CONEXA Investigacion Clinica S.A.
Buenos Aires, 1012, Argentina
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California Dermatology & Clinical Research Institute
Encinitas, California, 92024, United States
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Centre de Recherche Saint-Louis
Sherbrooke, J1G 1X9, Canada
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Centro de Investigaciones Metabólicas (CINME)
Buenos Aires, C1056ABI, Argentina
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Centro de Investigaciones San Miguel
San Miguel, 1663, Argentina
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Centro de Pesquisas da Clínica IBIS
Salvador, 41820-020, Brazil
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DOM Centro de Reumatología
Buenos Aires, C1111, Argentina
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Dawes Fretzin Clinical Research Group, LLC
Indianapolis, Indiana, 46250, United States
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DeNova Research
Chicago, Illinois, 60602, United States
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Deluxe Health Center
Miami Lakes, Florida, 33014, United States
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Dermatology Affiliates Research Institute
Atlanta, Georgia, 30305, United States
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Dermatology Research Associates
Los Angeles, California, 90045, United States
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Dr. Samuel Sanchez PSC
Caguas, 00725, Puerto Rico
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Encore Medical Research
Hollywood, Florida, 33024, United States
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Equity Medical
New York, New York, 10023, United States
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Equity Medical - Bowling Green
Bowling Green, Kentucky, 42104, United States
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Eternal Springtime Dermatology
Thunder Bay, P7C 4Y7, Canada
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Faculdade de Medicina do ABC
Santo André, 09060-870, Brazil
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Foxhall Research Center
Chevy Chase, Maryland, 20815, United States
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Fundación Respirar
Buenos Aires, C1426ABP, Argentina
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Great Lakes Research Group, Inc.
Bay City, Michigan, 48706, United States
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Health Clinical Research
Miami, Florida, 33176, United States
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Hickory Dermatology Research Center
Hickory, North Carolina, 28602, United States
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Hospital São Lucas da PUCRS
Porto Alegre, 90610-000, Brazil
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IBPClin - Instituto Brasil de Pesquisa Clínica
Rio de Janeiro, 20241-180, Brazil
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INECO Neurociencias Oroño
Rosario, 2000, Argentina
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ISPEM - Instituto São José dos Campos em Pesquisas Médicas
São José dos Campos, 12243-280, Brazil
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Instituto de Investigaciones Clinicas Rosario
Rosario, S2000CVD, Argentina
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Instituto de Neumonologia Y Dermatologia
Buenos Aires, C1425BEA, Argentina
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Irmandade da Santa Casa de Misericórdia de Porto Alegre
Porto Alegre, 90050-170, Brazil
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Jordan Valley Dermatology & Research Center
South Jordan, Utah, 84095, United States
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Kanata Allergy Clinic
Ottawa, K2T 0N7, Canada
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Leading Edge Dermatology
Plantation, Florida, 33317, United States
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Life Arc Research Centers - Miami
Miami, Florida, 33126, United States
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Lovegrove Dermatology
London, N6A 5R9, Canada
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MCR Research
Miami, Florida, 33126, United States
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Maritime Dermatology
Halifax, B3K 5R3, Canada
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NorCal Clinical Research
Rocklin, California, 95765, United States
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North York Research Inc
Toronto, M2N 3A6, Canada
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ObjectiveHealth - Goodlettsville Dermatology Research
Goodlettsville, Tennessee, 37072, United States
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PUC Trials- Nucleo de Pesquisa clinica da Escola de Medicina da PUCPR
Curitiba, 80230-130, Brazil
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Parra Dermatología
Mendoza, 5500, Argentina
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Prime Clinical Research - Mansfield
Mansfield, Texas, 76063, United States
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Psoriahue
Buenos Aires, C1425DKG, Argentina
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Renstar Medical Research
Ocala, Florida, 34470, United States
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Research Solutions of Arizona
Litchfield Park, Arizona, 85340, United States
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Reveal Research Institute - Frisco
Frisco, Texas, 75033, United States
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Revival Research Institute, LLC
Troy, Michigan, 48084, United States
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SKiN Centre for Dermatology
Peterborough, K9J 5K2, Canada
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Skin Care West
Nanaimo, V9V 1A3, Canada
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Solutions Through Advanced Research
Jacksonville, Florida, 32256, United States
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Southern Indiana Clinical Research Center
Columbus, Indiana, 47201, United States
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Southern Indiana Clinical Trials
New Albany, Indiana, 47150, United States
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Suncoast Research Associates
Doral, Florida, 33172, United States
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Texas Dermatology and Laser Specialists - San Antonio - South New Braunfels Avenue
San Antonio, Texas, 78235, United States
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Total Skin & Beauty Dermatology Center, PC DBA Total Dermatology
Birmingham, Alabama, 35203, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lebrikizumab (a drug injected under the skin)
What this could lead to
If it works, this could offer a new option for people with eczema who have severe itching even with limited skin involvement.
What could go wrong
This is an early-phase, open-label study with no placebo group, so results may be less reliable. It also only includes people with moderate eczema, so findings may not apply to severe cases.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.