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Herbal formula aims to stop bladder Cancer's return
NCT ID NCT07728474
First seen Jul 27, 2026 · Last updated Jul 30, 2026 · Updated 3 times
Summary
This trial tests whether an oral herbal supplement called LCS103 can help prevent non-muscle invasive bladder cancer from recurring after surgery. Sixty adults who have had their bladder tumors completely removed will take either LCS103 plus standard care or standard care alone for one year. The study will track safety and how well the supplement works at keeping the cancer away.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- an oral herbal formula called LCS103
- What this could lead to
- If it works, this could offer a simple, non-invasive way to reduce the risk of bladder cancer returning after surgery.
- What could go wrong
- This is an early-phase trial with only 60 participants, so results may not apply widely. The herbal formula may cause side effects or fail to prevent recurrence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men and women aged ≥ 18 years. * Non-muscle invasive urothelial carcinoma, histologically confirmed by TURBT procedure within 3 months before enrollment. * Complete resection of bladder tumor in recent TURBT. Exclusion Criteria: * Inability to provide informed consent. * Inability to swallow tablets (esophageal stricture, feeding through gastrostomy). * Ineligibility for SOC therapy such as BCG instillations (where appropriate). * Upper tract urothelial carcinoma within the past 2 years. * Any malignancy other than NMIBC, active or systemically treated within the past 2 years (not including localized cutaneous basal cell or squamous cell carcinoma). * Estimated life expectancy \< 5 years. * Pregnant women, and women planning future pregnancy or wishing to preserve fertility. * Investigator evaluation of a physical or mental condition limiting a patient's ability to participate in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Rambam Health Care Campus, Urology Department
RECRUITINGHaifa, Israel
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can heated saline during bladder surgery stop tumors from coming back?
- Can a bladder rinse before surgery keep bladder cancer at bay?
- Can a home care plan ease bladder cancer treatment side effects?
- Can a new drug help keep bladder cancer at bay?
- Can heated chemotherapy beat bladder cancer without surgery?
- Could a simple urine test spare bladder cancer patients from chemotherapy?