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First human trial launches for promising lassa fever vaccine

NCT ID NCT06546709

First seen Nov 16, 2025 · Last updated May 24, 2026 · Updated 23 times

Summary

This study tests a new vaccine called LASSARAB that aims to prevent Lassa fever, a serious viral illness common in parts of West Africa. The vaccine uses a modified rabies virus to deliver the Lassa antigen and includes an adjuvant to boost the immune response. About 55 healthy adults aged 18 to 50 will receive two doses to check for safety, side effects, and immune response. This is the first time this vaccine is being tested in humans.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Maryland, Baltimore, University of Maryland School of Medicine, Center for Vaccine Development and Global Health

    Baltimore, Maryland, 21201, United States

Conditions

Explore the condition pages connected to this study.