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Laser vs. scaler: which works better for infected implants?

NCT ID NCT06890117

Disease control Sponsor: Aristotle University Of Thessaloniki Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two non-surgical ways to treat peri-implantitis, an infection around dental implants. Forty patients were split into two groups: one received standard ultrasonic cleaning with saline, the other got a combination of Er:YAG and diode lasers. Researchers measured gum pocket depth, bleeding, bacteria levels, and pain over three months to see which approach worked better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Er:YAG (2940nm) and Diode (808nm) laser
What this could lead to
If it works, this could offer a less invasive way to treat peri-implantitis, reducing gum inflammation and saving dental implants without surgery.
What could go wrong
This is a small, short-term study (40 people, 3 months) comparing two non-surgical methods. Results may not apply to all cases, and laser treatment might not outperform standard cleaning.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jan 2025

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients presenting at the Postgraduate Periodontology Clinic with a diagnosis of peri-implantitis in at least one implant, based on the 2018 Classification of Periodontal and Peri-Implant Diseases (EFP 2018). * Probing pocket depth (PPD) of up to 10 mm. * Periodontally healthy individuals (no active periodontal disease). * Implants must have been in function (loaded) for at least one year. * Age ≥ 18 years. * Medically healthy individuals or those with well-controlled systemic conditions. * Implant-supported restorations must be accessible for proper oral hygiene. * Patients must provide signed informed consent for participation. * Non-smokers only Exclusion Criteria: * Presence of systemic diseases or medications that could influence treatment outcomes (e.g., uncontrolled diabetes, chemotherapy, immunosuppression). * Underwent peri-implantitis treatment in the past 3 months. * Use of antibiotics or antimicrobial therapy in the past 3 months. * Pregnancy or breastfeeding. * Smokers

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Peri-implantitis

Contacts and locations

Locations

  • Aristotle University of Thessaloniki

    Thessaloniki, 54124, Greece

More trials for these conditions

Other studies related to the condition(s) this trial covers.