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Laser light shows promise for healing numb lips after dental surgery

NCT ID NCT07416006

Symptom relief Sponsor: Ondokuz Mayıs University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether low-level laser therapy (using Nd:YAG or diode lasers) can help repair nerve damage in the lower jaw after dental procedures like wisdom tooth removal or implant placement. Thirty adults with numbness or tingling in their lower lip and chin received laser treatments twice a week for three weeks. The goal was to see if the laser could improve sensation and speed up nerve recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Low-level laser therapy (Nd:YAG and diode lasers)
What this could lead to
If successful, this could point toward a noninvasive way to speed up nerve healing and reduce numbness or tingling after oral surgery.
What could go wrong
This is a small, completed trial with only 30 people. Results may not apply to everyone, and laser therapy might not work better than natural healing or other treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Oct 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. Patients diagnosed with inferior alveolar nerve injury following intraoral surgical procedures (such as sagittal split osteotomy, implant placement, or third molar extraction) or mandibular trauma. Presence of sensory disturbances including anesthesia, hypoesthesia, or paresthesia in the lower lip and chin region. Ability and willingness to participate in the study and attend all scheduled follow-up visits. Provision of written informed consent prior to participation. Exclusion Criteria: * History of systemic diseases that may affect nerve healing (e.g., diabetes mellitus, neuropathies, autoimmune disorders). Current use of medications known to interfere with nerve regeneration (e.g., corticosteroids, neurotoxic drugs). Previous laser therapy or photobiomodulation treatment to the same area. History of smoking or alcohol abuse. Pregnant or breastfeeding women. Patients with local infection, malignancy, or open wounds in the treatment area. Inability to comply with study procedures or follow-up schedule.

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Conditions

The condition(s) this trial relates to.

Hypesthesia Paresthesia traumatic neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diode laser therapy Inferior alveolar nerve injury ND:yag laser biostimulation Nerve regeneration Neurosensory disturbance Oral and maxillofacial surgery complications Paresthesia and hypoesthesia Photobiomodulation therapy Post-surgical nerve recovery

Contacts and locations

Locations

  • Ondokuz Mayıs University, Faculty of Dentistry, Department of Periodontology

    Samsun, 55270, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.