Can a laser and green dye erase early tooth spots?
NCT ID NCT07818655
First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time
Summary
Researchers at Al-Azhar University are testing whether a diode laser combined with a green dye and a remineralizing agent can reduce the surface area of white spot lesions on teeth. The trial enrolls 90 people aged 13 to 40 who have good oral hygiene and no other health conditions. Dentists apply the treatment, then take digital X-rays and use subtraction imaging to measure any change in the lesion size.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a remineralizing agent applied with a diode laser and a green dye
- What this could lead to
- If it works, this could give dentists a way to shrink early white spot lesions without drilling, helping patients avoid fillings.
- What could go wrong
- This is a small, single-center study with no phase label, so results may not hold up in larger groups. The laser and dye add time and cost, and some lesions may not respond.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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90 people
The number who actually took part.
- Started
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May 2022
- Finished
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Apr 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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13 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: The patients should be 13e40 years old. The patients should have good oral hygiene, general health, and no systemic disease. Exclusion Criteria: presence of enamel hypoplasia, dental fluorosis, and carious cavity. These patients have diminished salivary flow or significant tooth wear, and concurrent participation in other clinical trials
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
ALAzaher
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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