New test may spot hidden throat reflux
NCT ID NCT01854970
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 30 people with symptoms of laryngopharyngeal reflux (LPR), such as hoarseness or a lump in the throat, and compared their pH-impedance test results to healthy individuals. The goal was to see if this test can better detect LPR. Participants took the drug esomeprazole for 8 weeks to see how symptoms and test results changed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- esomeprazole
- What this could lead to
- If successful, this could improve how doctors diagnose laryngopharyngeal reflux, leading to better treatment decisions.
- What could go wrong
- This is a small, completed study with only 30 participants, so results may not apply to everyone. It focuses on diagnosis, not a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
-
May 2013
- Finished
-
Jul 2015
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age : 18 to 80 years old. * Written consent * Laryngopharyngeal symptoms (dysphonia, and/or globus and/or sensation, and/or pharyngeal pain, and/or cough) for 3 months at least. * No PPI for at least 15 days * Social security affiliation Exclusion Criteria: * Sinusitis or chronic rhinitis (in the previous year) * Laryngeal trauma, tracheotomy or pharyngolaryngeal surgery * pregnancy or absence of efficacy contraception * breast feeding * history of gastrointestinal pathology, diabetes, neurological condition * cardio-vascular history requiring the taking of Plavix * esomeprazole contraindication or intolerance
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Laryngopharyngeal reflux are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU de Bordeaux
Bordeaux, 33000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.