New test may spot hidden throat reflux in patients with chronic symptoms
NCT ID NCT01854970
First seen May 15, 2026 · Last updated Jun 19, 2026 · Updated 6 times
Summary
This study looked at whether a special pH-impedance test placed in the throat and esophagus can better detect laryngopharyngeal reflux (LPR) in people with chronic throat symptoms like hoarseness, lump sensation, or cough. Thirty adults with suspected LPR and healthy volunteers underwent the test before and after 8 weeks of treatment with the acid-reducing drug esomeprazole. The goal was to compare results and see if the test helps identify who truly has LPR.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU de Bordeaux
Bordeaux, 33000, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
esomeprazole
What this could lead to
If successful, this could help doctors better diagnose laryngopharyngeal reflux using pH-impedance testing, leading to more targeted treatment.
What could go wrong
This is a small, completed study with only 30 participants, so results may not apply to everyone. The main goal is to improve understanding, not to prove a new treatment works.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.