Keyhole vs open surgery: which is better for periampullary cancer?
NCT ID NCT05788029
First seen May 26, 2026 · Last updated Jun 23, 2026 · Updated 5 times
Summary
This study compares two surgical techniques—laparoscopic (keyhole) and open surgery—for treating a rare cancer called nonpancreatic periampullary adenocarcinoma. About 212 patients will be randomly assigned to one of the two procedures. The main goal is to see which approach leads to a shorter hospital stay, while also tracking survival, complications, and blood loss.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Department of Biliary and Pancreatic Surgery, Tongji Hospital, Affiliated Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could show that laparoscopic surgery is as safe and effective as open surgery, potentially leading to shorter hospital stays and faster recovery for patients.
What could go wrong
This is a single-center study with 212 participants, so results may not apply to all hospitals or patients. The trial is not blinded, which could introduce bias.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.