New hope for brain cancer: experimental drug LAM561 tested in 144 patients
NCT ID NCT04250922
First seen Nov 20, 2025 · Last updated Apr 30, 2026 · Updated 23 times
Summary
This study tests whether adding the experimental drug LAM561 to standard radiation and chemotherapy can help people with newly diagnosed glioblastoma, an aggressive brain cancer. About 144 adults aged 18 to 75 will receive either LAM561 or a placebo alongside their usual treatment. The goal is to see if LAM561 can slow tumor growth and extend survival.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cambridge university hospital
Cambridge, United Kingdom
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Centre Eugène Marquis (CEM)
Rennes, France
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Freeman Hospital's Northern Centre of Cancer Care
Newcastle, Newcastle Upon Tyne, NE7 7DN, United Kingdom
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Gustave Roussy University Hospital
Rennes, France
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Hospital Clinic
Barcelona, Barcelona, Spain
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Hospital Clínico San Carlos
Madrid, Madrid, Spain
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Hospital Parc Tauli
Sabadell, Spain
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Hospital Universitari i Politécnic La Fe.
Valencia, Valencia, 46026, Spain
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Hospital Universitario 12 De Octubre
Madrid, Spain
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Hospital Universitario Reina Sofía
Córdoba, Andalusia, Spain
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Hospital Universitario Virgen del Rocío
Seville, Andalusia, Spain
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Hospital Vall d'Hebron
Barcelona, Barcelona, Spain
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Hospital del Mar
Barcelona, Spain
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Institut Cancerologie de L'Ouest (ICO)
Angers, France
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Institut universitaire du cancer
Toulouse, France
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Istituto Nazionale Neurologico Carlo Besta
Milan, Italy
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Istituto Nazionale Tumori "Regina Elena"
Roma, Italy
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Istituto Oncologico Veneto IRCCS
Padova, Veneto, 35131, Italy
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Reaserch Fund of the Hadassah Medical Organization
Jerusalem, Israel
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The Royal Marsden Hospital
London, United Kingdom
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University Hospitals Birmingham NHS Foundation Trust - New Queen Elizabeth Hospital
Birmingham, United Kingdom
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University of Turin
Turin, Italy
Conditions
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