Placenta injection may ease shoulder pain
NCT ID NCT05528705
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether an injection made from human placenta, called LAENNEC, can reduce shoulder pain in people with shoulder impingement syndrome. 50 adults with shoulder pain received either the LAENNEC injection or a placebo, guided by ultrasound. The main goal was to see if pain scores improved.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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50 people
The number who actually took part.
- Started
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Sep 2022
- Finished
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Jan 2024
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. At the time of screening, 19 or 70 years 2. Those who are suspected of rotator cuff lesions or damage due to shoulder pain 3. Those who are judged to have a shoulder joint disease during screening 4. Neer test, Hawkins-Kennedy inspection, job test, Painful Arc inspection or resisted showder external rotation test 5. Those with a significant pain of 30 mm of Visual Analogue Scale (VAS) 6. Those who can sign a test subject or to comply with the matters required for clinical trials. Exclusion Criteria: 1. A person who appears in the movement of two or more shoulder joints with more than 50% of the joint movement limit on the passive shoulder joint operation scope test. 2. Those who have confirmed the rupture of the entire layer by ultrasound 3. Those with serious damage to the shoulders and the past power 4. Those who have suspected fractures, dislocations, degenerative arthritis, and calcification in the shoulder radiation test in the shoulder radiation test. 5. Those who complain of shoulder pain due to stroke, spinal cord injury, and other surgery 6. Those with other shoulder diseases other than fifty dogs (rheumatoid arthritis, osteoarthritis, bone defect injuries, malignant tumors, etc.) 7. Those who are accompanied by diseases of cervical spine or other upper limbs that have a significant effect on the shoulder 8. Those who have performed steroid injections in the joint steel within 3 months of participation in clinical trials 9. Those who have administered anti -inflammatory drugs within two weeks of participation in clinical trials 10. Those with all other joint diseases that have musculoskeletal diseases that may affect effective evaluation, or that it is impossible to participate in this clinical trial. 11. Those who are diagnosed with mental illness and taking drugs 12. Pregnant women and lactation departments, fertility women who are not willing to contraceptive during the clinical trial period 13. Those who have received medication, oriental medicine, physical therapy, and injection treatment in relation to shoulder pain within the last two weeks 14 Those who are participating in other clinical trials during screening 15\. Those who determine that other testors are inadequate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chung-Ang University Gwangmyeong Hospital
Gwangmyeong, South Korea
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Chung-Ang University Hospital
Seoul, South Korea
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Keimyung University Dongsan Hospital
Daegu, South Korea
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Other studies related to the condition(s) this trial covers.
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