Natural prebiotic could beat antibiotics for thrush and BV
NCT ID NCT05434104
First seen Mar 26, 2026 · Last updated Jun 19, 2026 · Updated 9 times
Summary
This study tests whether lactoferrin, a natural prebiotic from cow's milk, can be a good alternative to antibiotic tablets for women with bacterial vaginosis (BV) or thrush. Researchers will recruit 114 women and give half lactoferrin vaginal pessaries for 3 weeks, while the other half gets standard oral antibiotics. The goal is to see if women find lactoferrin acceptable and if it works well enough to justify a larger future trial.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Guy's and St Thomas' Sexual Health Clinic
RECRUITINGLondon, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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St Thomas' NHS Trust
NOT_YET_RECRUITINGLondon, se1 7eh, United Kingdom
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lactoferrin vaginal pessaries
What this could lead to
If it works, this could offer women a natural, antibiotic-free option for treating common vaginal infections, reducing side effects and antibiotic resistance.
What could go wrong
This is a small feasibility study, not a large trial. Lactoferrin may not work as well as standard antibiotics, and infections could return.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.