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Could a milk protein boost your iron and workout? study investigates

NCT ID NCT06428357

Knowledge-focused Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a supplement called recombinant bovine lactoferrin (rbLf) can help regulate iron levels, improve gut health, and boost exercise performance in healthy adults. About 110 active men and women took rbLf, regular lactoferrin from cow's milk, or a placebo daily for four weeks. Researchers measured changes in blood iron, red blood cells, and treadmill running time to see if the supplement made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Recombinant bovine lactoferrin (rbLf) supplement
What this could lead to
If it works, this could point toward a dietary supplement that helps healthy people manage iron levels and improve exercise performance.
What could go wrong
This is a small, early-stage study in healthy adults, so results may not apply to people with iron problems. The supplement may show no benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

92 people

The number who actually took part.

Started

Jul 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 42 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-42 years * Body mass index less than 35 kg/m\^2 * Finger prick hemoglobin levels fitting within "normal range" * Males: 14-18g/dL * Females: 12-16g/dL * Active: meeting American College of Sports Medicine exercise guidelines or exercising more than 2 days per week of ● For females specifically: * Pre-menopausal: experiencing a regular period with no signs of perimenopause or menopause. Exclusion Criteria: * Clinically diagnosed iron-deficiency anemia, pagophagia, hemochromatosis, or other blood or iron related medical conditions. * Allergy or intolerance to milk, egg, soy, peanut, wheat, coconut, or almond dairy * Smokers or vapers of nicotine or nicotine products * Immunocompromised or diagnosed with Type I or II diabetes * Irritable Bowel Disease, Crohn's disease, Celiacs * Bowel movements less than three times per week, or clinically constipated * Oral contraceptive users that have combined iron supplementation, or non-monophasic oral contraceptive users. * Pregnant or nursing * Chronic eczema or clinically diagnosed asthma. * Current antibiotic use or antibiotic use within the past 6 weeks * If flu, corona virus, or cold occurs, subject will remain in the study with their original scheduled visits, but immune values will be excluded. * Vegan (due to supplement ingredients).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise performance

Contacts and locations

Locations

  • Applied Physiology Laboratory

    Chapel Hill, North Carolina, 27599, United States

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