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Amino acid supplement may boost brain health in depressed seniors

NCT ID NCT07497347

First seen Apr 07, 2026 · Last updated May 20, 2026 · Updated 6 times

Summary

This study tests whether taking L-serine, a natural amino acid supplement, for 48 weeks can improve thinking, mood, and brain function in older adults (ages 65-85) with late-life depression. Half of the 84 participants will receive L-serine and half a placebo. Researchers will measure changes in depression, memory, and quality of life, and look at brain activity and gut bacteria to understand how L-serine might work.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS Centro San Giovanni di Dio Fatebenefratelli

    RECRUITING

    Brescia, 25125, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.