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Dental implant breakthrough: sticky bone may beat PRF alone

NCT ID NCT07433920

Disease control Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests three ways to fill the gap between a tooth root and a new dental implant placed right after tooth removal. The methods are: a blood concentrate (L-PRF), a mix of the patient's own tooth particles with PRF (sticky tooth), or a mix of bone graft with PRF (sticky bone). About 45 adults with a failing front tooth will get one of these treatments during computer-guided implant surgery. The goal is to see which method keeps the bone and gums most stable over 6 months.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Medically healthy patients according to the American Society of Anesthesiologists (ASA) physical status classification system; only patients belonging to ASA I and ASA II categories will be included in this study. * Age \> 18 years. * Patients presenting with one non-restorable hopeless anterior tooth due to extensive caries, cervical/root fracture, vertical or oblique root fracture, multiple failed endodontic treatments, or root resorption. * Sufficient apical/palatal bone to obtain primary implant stability. Exclusion Criteria: * Patients belonging to ASA III, ASA IV and ASA V will be excluded. * Vertical root fracture involving the labial aspect of the root planned to be retained as the facial shield. * Horizontal root fracture that is too far apically located. * Presence of acute (active) periapical infection. * Large chronic periapical lesion. * Lack of sufficient bone apical to the extraction socket to obtain primary stability. \* Ankylosed tooth positioned too apically in relation to adjacent teeth.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental implant failed

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Walid Elamrousy

    RECRUITING

    Kafr ash Shaykh, 76130, Egypt

  • faculty of dentistry, kafrelsheikh University

    RECRUITING

    Kafr ash Shaykh, Kafrelsheikh, 214312, Egypt

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