New combo therapy aims to stabilize AML longer
NCT ID NCT04190550
First seen Jan 05, 2026 · Last updated May 19, 2026 · Updated 29 times
Summary
This early-phase trial studies the safety and best dose of navtemadlin when added to standard chemotherapy (cytarabine and idarubicin) for people with newly diagnosed acute myeloid leukemia (AML). Navtemadlin blocks a protein that helps cancer cells grow. The goal is to see if the combination can keep the cancer stable longer than chemo alone. About 24 adults will take part.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016, United States
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201, United States
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University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
Conditions
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