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New shot-and-pill combo aims to calm facial nerve pain

NCT ID NCT07596485

First seen May 20, 2026 · Last updated May 24, 2026 · Updated 1 time

Summary

This early-stage study tests whether an injection of KRIYA-748 followed by a daily varenicline pill is safe and can reduce pain and attack frequency in people with trigeminal neuralgia, a condition causing severe facial pain. About 24 adults with classic trigeminal neuralgia will receive the treatment and be monitored for side effects and pain changes. The goal is to find a tolerable dose and see if the combination offers meaningful relief.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kriya Clinical Study Site

    RECRUITING

    Sherbrooke, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.