Knee replacement recovery: which pain block gets you home faster?
NCT ID NCT05715645
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 130 people having knee replacement surgery for osteoarthritis. It compared two ways to manage pain: one using a nerve block near the knee, and the other adding extra numbing medicine around the joint. The goal was to see which method helped patients recover faster and meet the criteria to leave the hospital sooner.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- adductor canal block and peri-articular infiltration
- What this could lead to
- If successful, this could show a better way to manage pain after knee replacement, helping patients recover faster and go home sooner.
- What could go wrong
- This is a small, completed study comparing two established techniques, so it may not lead to major changes in practice. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
130 people
The number who actually took part.
- Started
-
Apr 2023
- Finished
-
Mar 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient with a score "American Society of Anesthesiologists" I to III; * Patient undergoing initial unilateral prosthetic knee replacement surgery for osteoarthritis; * Patient eligible for analgesia by block of the adductor canal associated with additional infiltration; * Patient accepting to follow the enhanced recovery program after surgery; * Patient who signed an informed consent form to participate in the study. Exclusion Criteria: * Patient with a known allergy to a study product; * Patient having undergone previous surgery with a prosthesis on the knee to be operated on; * Patient with morbid obesity (Body Mass Index \> 40); * Patient with a pre-existing inability to walk; * Patient with a history of chronic neuropathic pain in the leg undergoing surgery; * Patient with heart failure with impaired ejection fraction; * Patient with a history of drug addiction; * Patient chronically taking level III analgesics; * Patient taking gabapentin or pregabalin chronically; * Patient with severe renal or hepatic impairment; * Patient with a high level of dependence, defined by level 1 or 2 of the Iso-Ressources Group; * Protected patient (under legal protection, or deprived of liberty by judicial or administrative decision); * Patient unable to understand the information related to the study (linguistic, psychological, cognitive reasons, etc.); * Pregnant or likely to be pregnant (of childbearing age without effective contraception) or breastfeeding; * Patient participating in another clinical trial, or in a period of exclusion from another clinical trial; * Patient not benefiting from a social security scheme.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Unilateral primary osteoarthritis of knee are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hôpital Privé Médipôle
Villeurbanne, 69100, France