New pain combo may help knee replacement patients recover faster
NCT ID NCT07517159
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding a nerve block (adductor canal block) to standard local pain injections reduces pain after knee replacement surgery better than injections alone. 61 adults having knee replacement took part. The goal was to find a way to improve pain control and help patients move sooner after surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
61 people
The number who actually took part.
- Started
-
May 2025
- Finished
-
Nov 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 years and older * Patients scheduled for elective total knee arthroplasty * American Society of Anesthesiologists (ASA) physical status I-III * Patients who provided written informed consent Exclusion Criteria: * Known allergy to local anesthetics * Coagulation disorders or anticoagulant therapy contraindicating regional anesthesia * Infection at the injection site * Severe hepatic or renal dysfunction * Neurological disorders affecting lower extremities * Cognitive impairment preventing pain assessment * Refusal to participate * Body mass index (BMI) greater than 30 kg/m²
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Osteoarthritis, knee are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ankara University Faculty of Medicine, Ibni Sina Hospital
Ankara, Ankara, 06100, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which anesthesia gets joint replacement patients moving sooner?
- Can a special MRI match CT for spotting knee bone damage?
- Can a common bleeding drug make knee realignment surgery safer?
- One shot, new knee? gene therapy trial aims to quiet arthritis pain
- Three knee shots go Head-to-Head for lasting arthritis relief
- Gel shot vs standard injection: which quiets arthritic knees?